HostMySite offers Plesk as a default VPS Management Tool.
Plesk is designed to help IT specialists manage web, DNS, mail and other services through a comprehensive and user-friendly Graphical User Interface (GUI). Plesk is a hosting control panel, an intermediary between system services and users. For example, when a user creates a website through the Plesk GUI, Plesk propagates this request to a web server, either Apache or IIS, and the latter adds a new virtual host to the system. This method of administering all system services from a single web interface reduces maintenance costs and gives administrators more flexibility and control.
Plesk simplifies web management activities to align with the way infrastructure is used today for hosting websites and web applications. As the most widely used web management solution, Plesk provides everything a web professional needs to set up a website quickly and securely – including a WordPress Toolkit, an easy-to-navigate control panel, server level automation, supportability tools, and complete protection with our server-to-site security core.
For optional functionality you may also want to consider cPanel.